Abstract Background Evolutionary autonomous agents are robots or robot simulations whose controller is a dynamical neural network and whose evolution occurs autonomously under the guidance of a fitness function without the detailed or explicit direction of an external programmer.They are embodied agents with a simple neural network controller and a
Bullous skin diseases are a group of dermatoses characterized by blisters and bullae in the skin and mucous membranes.The etiology and pathogenesis of bullous skin diseases are not completely clear.The most common are pemphigus and bullous pemphigoid (BP).Autoantibodies play critical roles in their pathogenesis.Abnormalities in click here the adhes
We describe the production of collagen fibre bundles through a multi-strand, semi-continuous extrusion process.Cross-linking using an EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide), skull bride and groom NHS (N-hydroxysuccinimide) combination was considered.Atomic Force Microscopy and Raman spectroscopy focused on how cross-linking affected th
IntroductionThe main challenge for cancer therapy lies in immuno-suppressive tumor micro-environment.Reprogramming tumor-associated macrophages (TAMs) into an anti-tumor phenotype is a promising strategy.MethodsA comprehensive analysis by combing multi-regional single-cell, bulk and spatial transcriptome profiling with radiomics characterization wa